Lance Simpson's Botulinum Neurotoxin and Tetanus Toxin PDF

By Lance Simpson

ISBN-10: 0124122477

ISBN-13: 9780124122475

ISBN-10: 0126444455

ISBN-13: 9780126444452

Botulinum Neurotoxin and Tetanus Toxin covers the mechanism of motion, pathogenesis, and therapy of clostridial neurotoxins. The publication is prepared into 4 components encompassing 18 chapters that debate the foundation, constitution, pharmacology, toxicology, immunology, assays, and scientific problems with botulinum and tetanus neurotoxins.
The introductory a part of the booklet discusses the invention and creation of neurotoxins in quite a few lines of Clostridium micro organism. this article additionally describes how particular bacteriophages and plasmids mediate the pathogenicity of a few different types of Clostridium botulinum and Clostridium tetani. the following half offers an outline of matters with regards to toxin binding, together with pollutants that could function types for botulinum and tetanus neurotoxins. Discussions at the peripheral and vital features of poisoning shipping within the critical apprehensive approach and at the hostile medicines for clostridial neurotoxins are supplied. The 3rd a part of the booklet addresses the antibodies opposed to botulinum neurotoxin. Bioassay in mice and hugely delicate immunoassays, similar to reversed passive hemagglutination, reversed passive latex agglutination, radioimmunoassay, and enzyme-linked immunosorbent assay, are offered. The concluding half covers the animal types for those pollutants and discusses the analysis and therapy of botulism and tetanus in human. The scientific use of Clostridium botulinum toxin variety A in ocular and neuromuscular sickness can also be tested.
This e-book may be of price to protein chemists, microbiologists, virologists, pharmacologists, immunologists, and clinicians.

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Botulinum Neurotoxin and Tetanus Toxin by Lance Simpson


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